Friendlies
- Alisohn Nilesia - Factol of the Mercykillers
- Allisanaa Boughbender - Innkeeper of the Drunken Leaf
- Alziel - Guardian of the Arch of Triumph
- A'kin - Owner of the Friendly Fiend
- Amadeus - Mimic "pet"
- Arwyl Swan's Son - Factor of the Mercykillers
- Bendon Mawl - Fated Underboss
- Breath of Life - Allisiphone's Mortai friend
- Cauldronborn - Interim Mayor of Heart's Faith
- Derioch Ysarl - Bleak Cabal Liason
- Duke Rowan Darkwood - Factol of the Fated
- Erin Montgomery - Factol of the Society of Sensation
- Greir Crasad - Crusader of the Planes-Militant
- Heiron Lifegiver - Talented Artificer
- Immolien Boughbender - Proxy of Corellon Larethian
- Jamis - Factor of the Fraternity of Order
- Lebes - Mayor of Heart's Faith
- Komosahl Trevant - Factor of the Dustmen
- Mimi Whitecastle - Jocelyn's Sensate sponsor
- Sir Ulric* - Paladin of the Order of the Planes-Militant
- Sir Vaimish Crasad - Lord Protector of Excelsior
- Skall - Factol of the Dustmen
- Xaldra Miloni* - Friend of Quicksilver
- Ydemi Jysson - Cat Petitioner
Neutrals
- Alvion* - Barmy victim
- Ambar Vergrove - Factol of the Believers of the Source
- Bria Tomay - "Factol"/Leader of the Free League
- Clarent - Barmy victim
- Darius the Veyl - Factol of the Transcendent Order
- Denrac Grundarein* - Mate of Yissa Nyclar
- Eldrad Moore - Gnome witness to Xaldra's abduction
- Harold - Harmonium Guard
- Hashkar - Factol of the Fraternity of Order
- Isel Three-thumbs - Bariaur witness to Xaldra's abduction
- Karan - Factol of the Xaositects
- Lhar - Factol of the Bleak Cabal
- The Lady of Pain - "Ruler" of Sigil
- Mordrigaarz Antill - Factor of the Xaositects
- Mourner Tom and the Collectors - Hive body collectors
- Muenscaal - Friend of Heiron Lifegiver
- Pentar - Factol of the Doomguard
- Rhys - Factol of the Transcendant Order
- Rickshaw - Githyanki troublemaker
- Salja - Black Sail Barmaid
- Sarin - Factol of the Harmonium
- Shillman - Barmy victim
- Temmilar Isquain - Tiefling witness to Xaldra's abduction
- Terrance - Factol of the Athar
- Thandol - Cooked Meat Proprietor
- Tourlac - Proprietor of the Divine Machine
- Three-Teeth - Owner of The Butcher's Block
- Tylaric Stormwing aka "The Dancing Man" - 1st "victim"
- Ulfwood - Barmy victim
- Zaren - Owner of The Black Sail
Villains
- Alver Kend* - Illuminated Priest
- Brandal* - Illuminated Priest
- Green Marvent - Leader of the Illuminated
- Hurfang* - Hobgoblin Chief
- Ildurn Grimm - Leader of Valran's Bleaker mercenaries
- Illurien - Villain in Campaign's Macguffin event
- Imogen* - Castellan of the Citadel of Fire
- Jezrene the Quickeye* - Council of Anarchy "Problem-solver"
- Kr'klckl* - Fire Grue Mercenary
- Leggis Scrog - Council of Anarchy leader
- Margram* - Illuminated Priest
- Orcus* - Archdemon
- The Shadowknave* - Murderer in the Hive
- Sargonnas - God of Vengeance
- Sethetis* - Tacharim Priest
- Talmizar - Leader of the Sorcerer-Kings
- Tenebrous - Orcus "reborn"
- Toranna the Gray* - Dustman Coroner's Assistant
- Trent* - Captain of the Guard - Citadel of Fire
- Valran Stonefist - Inventor of Modronoid creation
- Xaldra the Modronoid - The modron-grafted hybrid of Xaldra
- Yissa Nyclar*
Monsters
- Aasimar
- Archon, Lantern
- Archon, Sword
- Bariaur
- Dracolich, Ancient
- Dustmen Guardian
- Githzerai
- Half-Elf
- Human
- Fire Grue
- Lammasu
- Lich
- Linnorm, Ice
- Modron, Monodrone
- Modron, Duodrone
- Modron, Tridrone
- Modron, Quadrone
- Modron, Pentadrone
- Modron, Decaton
- Modron, Nonaton
- Modron, Octon
- Modron, Septon
- Modron, Hexton
- Modron, Quinton
- Mummified Lord
- Riding Lizard
- Skeleton
- Stone Golem
- Undying Sentry
- Yeth Hound
- Zombie
Templates
- "*"Denotes individual is deceased or presumed dead.